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Jensen (1987) repeated these early studies and presupposed new estimations. She did not find that border product of the research expenditures depended on the firm size. She results suggests instead of that, except the smallest enterprises, there is no certain advantage for new products of each large research to scale or large firm size. The present literature on this topic advanced studies beyond these early. Much of the progress is the work of Cockburn and of Henderson zuzuschreibend, which emphasize differences between the discovery and the development of the new drugs (2001, P. 3). Discovery includes the fundamental science and the application of the science to allotters of the applicant drugs. In this effort the research process in this only some applicant drugs is continued really in development particularly riskily. Drug development on the other hand closes largely the three phases of the examination required by the FDA. Although results are safe as forwards, it remains a risky process, in which many future drugs are thrown away. Although development has the segment of the pharmaceutical research few a scientific component as the discovery phase, it remains a substantial assumption, which absorbs more than half of the total industrial research budget. Cockburn and Henderson (2001, P. 6) report that the relative costs of development explained efforts between 60% and 70% of pharmaceutical research activities since 1970. The costs of this work are determined largely by FDA requirements. For their original investigation on this topic, Henderson and Cockburn (1996) seized horizontally aligned data of the project of 10 large pharmaceutical companies, which together approximately a quarter of total industrial research and development explained. If their data are accumulated to the firm level, report them on no proof of the scale national economy: "the implied long-term elasticity of the important patent gave expenditure in each model regarding research was between 0.4 and 0.5" out (P. 46). However their analysis of programlevel data leads it to the different summaries. Although it "on rather sharply decreasing limited return to increasing investment in each individual program report. . the programs, which are embedded in the larger and varied enterprises, seem, clearly more productive to be "(P. 48). Therefore they find to cost degression and range on the firm level. Cockburn and Henderson (2001) confirm that their early results concern only the discovery phase of the pharmaceutical research and not for development. In order to repair for this omission, they seized additional data of the same 10 companies, which had early examined them. These information the national economy of research and of development 65 was for 708 development of projects led between 1960 and 1990.