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While its preceding study estimated R&D expenditures per new drug with $231 million in 1987 dollar, her newer one supplies an estimation of $802 million to 2000 dollar. These illustrations indicate sharply higher costs of development of new products. From this favorable point in addition, the growth of one did not reduce science based research effort, did not lead research costs however to the higher. VI. The efficiency of the pharmaceutical research: Some summaries are different perspectives there, from which evaluate the efficiency of the pharmaceutical research. One are whether the optimal quantity of research is led. Too many or too.few operational funds could be assigned to this purpose. A second measure is whether this research is accomplished in the most effective way, so that exit for given levels of the entrance is maximized. In this section I regard both this mass; first is designated allocative efficiency, and the second is designated technical efficiency. On the allocative efficiency of the pharmaceutical research, there are theoretical reasons, why there could be under it either or Overinvestment in the research. Onthe a hand, a researchactivities and particularly a basic research, produce substantial positive outward appearances by the fact that their total use exceeds to the society, which result to the certain enterprise. Consequently enterprises do not contain its full measure use, if they meet their investment decisions. On the other hand there is newer economic literature on current behavior regarding research activities. An important summary is in a "winner taking the all" situation, can Overinvestment there into the research activities be. The reason is that the future profits can be smaller than the total amount of the investment, which is taken up, in order to obtain these profits. Research expenditure in the pharmaceutical industry is accomplished in the context of the considerable interfirm rivalry. I main headers that point in my first article on this topic out (Comanor 1964) however presupposed no formal model of the process. Since this time it gave more formal discussions over these expenditures. A particularly clear one is offered by Cockburn andHenderson (1994), which emphasizes the competitive nature of the drug discovery process. The authors first report the existing theoretical literature on rivalrous research and emphasize its "winner taking all" characteristic.

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